Diagnostic value of serum survivin, Ki-67 and thymidine kinase in dogs with nasal cavity disease
Although not diagnostic for ND, increased survivin serum concentrations or SLR can be detected in dogs with malignant nasal tumors and IR. In malignant nasal tumors, survivin and SLR did not correlate with tumor size and therefore may be useful in the detection of even small nasal tumors. Therefore, in dogs with nasal tumors and IR, survivin and SLR could serve as a target for disease monitoring or as therapeutic target.
Authors
- Stephan Neumann (ORCID: https://orcid.org/0000-0002-8392-0093)
- Gerhard Oechtering (ORCID: https://orcid.org/0000-0002-2597-3234)
- Sarah Rösch (ORCID: https://orcid.org/0000-0003-0420-963X)
- Annkathrin Estaller (ORCID: https://orcid.org/0000-0003-0490-4819)
Institutions
- University of Göttingen (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-04-07
- DOI
- https://doi.org/10.3389/fvets.2025.1553551
- Primary Topic
- Veterinary Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Georg-August-Universität Göttingen