Protocatechualdehyde induced tumor suppressive autophagy through AMPK/ULK1 signaling pathway in gastric cancer
These findings demonstrated that PCA inhibited gastric cancer by inducing tumor suppressive autophagy through the AMPK/ULK1 signaling pathway. PCA may serve as a novel candidate for the treatment of gastric cancer.
Authors
- Xiaoyu Sun (ORCID: https://orcid.org/0000-0002-9468-8787)
- Mengmeng Qin (ORCID: https://orcid.org/0000-0001-9632-4509)
- Aiguang Zhao
- Ruohan Zhao
- Mingming Ren (ORCID: https://orcid.org/0009-0002-8261-0197)
- Jintao Zhu (ORCID: https://orcid.org/0000-0002-8230-3923)
- Yongfu Pan
- Yi Wang (ORCID: https://orcid.org/0000-0003-0797-5209)
- Yan Xu (ORCID: https://orcid.org/0000-0002-2636-7594)
- Yunchao Zhang (ORCID: https://orcid.org/0000-0002-3226-5324)
- Nida Cao
- Xiaohong Zhu
- Fangqi Ma
Institutions
- University of Science and Technology of China (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- The First People’s Hospital of Lianyungang (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.3389/fonc.2025.1563006
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35