Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy
Our HR MAS NMR-based approach identified metabolic signatures in prostate biopsies that reflect the response of benign tissues to the presence of nearby located tumors in the same prostate and confirmed the power of the TINT concept for improved PC diagnostics and understanding of tumor-tissue interactions.
Authors
- Gerhard Gröbner (ORCID: https://orcid.org/0000-0001-7380-8797)
- Pernilla Wikström (ORCID: https://orcid.org/0000-0002-6347-1999)
- Anders R. J. Bergh (ORCID: https://orcid.org/0000-0001-5163-5821)
- Ilona Dudka (ORCID: https://orcid.org/0000-0002-0153-7278)
- João Figueira (ORCID: https://orcid.org/0000-0001-8819-2278)
Institutions
- Umeå University (SE)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-04-07
- DOI
- https://doi.org/10.3389/fmolb.2025.1426949
- Citations
- 1
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52