Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature

The primary objective of this study is to identify and validate BRCA-associated FAMGs that can serve as prognostic indicators and provide insights into immune system function, while also offering evidence to support the development of fatty acid metabolism-related molecularly targeted therapeutics. Consequently, FAMGs and their interactions with the immune system, as well as their role in BRCA, may emerge as promising therapeutic targets.

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Publication Details

Journal
Hereditas
Published
2025-04-07
DOI
https://doi.org/10.1186/s41065-025-00425-4
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature

Zhaofeng Ma, Pulin Liu, Man Zheng
Hereditas
Cancer, Lipids, and Metabolism
article

Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature

Zhaofeng Ma, Pulin Liu, Man Zheng
article en

Abstract

The primary objective of this study is to identify and validate BRCA-associated FAMGs that can serve as prognostic indicators and provide insights into immune system function, while also offering evidence to support the development of fatty acid metabolism-related molecularly targeted therapeutics. Consequently, FAMGs and their interactions with the immune system, as well as their role in BRCA, may emerge as promising therapeutic targets.

HereditasVol. 162(1)
Shandong University of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 92%
Cancer, Lipids, and Metabolism
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