Therapeutic Challenges in the Management of <scp>VEXAS</scp> Syndrome: A Case Report

VEXAS syndrome is a newly described autoinflammatory and haematologic condition that has variable cutaneous and systemic presentations. We present a case of VEXAS syndrome in a 63-year-old male with treatment refractory pyoderma gangrenosum and a complex dermatologic and systemic history. We hope it informs and encourages dermatologists to consider early diagnostic testing for VEXAS syndrome in any male over 50 years of age with a neutrophilic dermatosis and unexplained autoinflammation.

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Publication Details

Journal
Australasian Journal of Dermatology
Published
2025-04-06
DOI
https://doi.org/10.1111/ajd.14478
Citations
1
Primary Topic
Otitis Media and Relapsing Polychondritis
Type
article
Field-Weighted Citation Impact
1.67
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article

Therapeutic Challenges in the Management of VEXAS Syndrome: A Case Report

Amanda Godbolt, Yolanka Lobo, Georgia Kelly Ferreira de Queiroz
1 citations
Australasian Journal of Dermatology
Otitis Media and Relapsing Polychondritis
1.67
article

Therapeutic Challenges in the Management of VEXAS Syndrome: A Case Report

Amanda Godbolt, Yolanka Lobo, Georgia Kelly Ferreira de Queiroz
article en
1 citations

Abstract

VEXAS syndrome is a newly described autoinflammatory and haematologic condition that has variable cutaneous and systemic presentations. We present a case of VEXAS syndrome in a 63-year-old male with treatment refractory pyoderma gangrenosum and a complex dermatologic and systemic history. We hope it informs and encourages dermatologists to consider early diagnostic testing for VEXAS syndrome in any male over 50 years of age with a neutrophilic dermatosis and unexplained autoinflammation.

Australasian Journal of DermatologyVol. 66(4)
Royal Brisbane and Women's Hospital (AU), Sunshine Coast University Hospital (AU)
Good health and well-being
Openalex Percentile: Top 19%
Otitis Media and Relapsing Polychondritis
1.67
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Therapeutic Challenges in the Management of <scp>VEXAS</scp> Syndrome: A Case Report — Amanda Godbolt, Yolanka Lobo, et al. · Australasian Journal of Dermatology (2025) | TGRS Research Map | TGRS