GINS1 facilitates the development of lung adenocarcinoma via Wnt/β-catenin activation
Our findings suggest that GINS1 plays a critical role in the progression of LUAD by modulating key molecular pathways, particularly the β-catenin signaling pathway., and it might serve as a potential new target of β-catenin signaling pathway for treatment of LUAD.
Authors
- Rongyang Li (ORCID: https://orcid.org/0000-0001-6047-3027)
- Pengyong Li (ORCID: https://orcid.org/0000-0001-5971-046X)
- Libo Si
- Wenhao Yu (ORCID: https://orcid.org/0009-0002-6168-1324)
- Luyuan Ma (ORCID: https://orcid.org/0000-0002-1816-5175)
- Hui Tian (ORCID: https://orcid.org/0000-0002-8932-3003)
- Zhanpeng Tang
Institutions
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1186/s12957-025-03786-2
- Citations
- 3
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Natural Science Foundation of China