Mechanistic insights into COVID-19 mRNA vaccine-associated myocarditis: a bioinformatics analysis

This study implicates immune dysregulation driven by CXCR3, NKG7, and GZMH in post-vaccination myocarditis, supported by regulatory networks and therapeutic insights using a bioinformatics analysis. These findings advance mechanistic understanding of this rare adverse event and propose potential treatment strategy for further investigation.

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Publication Details

Journal
American Journal of Translational Research
Published
2025-01-01
DOI
https://doi.org/10.62347/ccvm6311
Citations
1
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
1.39

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article

Mechanistic insights into COVID-19 mRNA vaccine-associated myocarditis: a bioinformatics analysis

Yanjie Jiang
1 citations
American Journal of Translational Research
Viral Infections and Immunology Research
1.39
article

Mechanistic insights into COVID-19 mRNA vaccine-associated myocarditis: a bioinformatics analysis

Yanjie Jiang
article en
1 citations

Abstract

This study implicates immune dysregulation driven by CXCR3, NKG7, and GZMH in post-vaccination myocarditis, supported by regulatory networks and therapeutic insights using a bioinformatics analysis. These findings advance mechanistic understanding of this rare adverse event and propose potential treatment strategy for further investigation.

American Journal of Translational ResearchVol. 17(3)
Shandong Provincial Hospital (CN), Taian City Central Hospital (CN)
Natural Science Foundation of Shandong Province
Zero hunger
Openalex Percentile: Top 21%
Viral Infections and Immunology Research
1.39
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