Immunological and histopathological changes in alkali burn-induced ocular surface pannus: Implication on success vs. failure of SLET
This study highlights a significantly higher infiltration of immune cells in the pannus and surrounding ocular tissue in cases of SLET failure compared to successful outcomes. These findings suggest that, strategies to reduce immune infiltration such as immunotherapy, corticosteroids, or amniotic membrane grafting should be considered prior to SLET to improve the success of limbal transplant surgery.
Authors
- Madhuri Amulya Koduri (ORCID: https://orcid.org/0000-0002-3375-9713)
- Sayan Basu (ORCID: https://orcid.org/0000-0001-5030-5003)
- Anahita Kate (ORCID: https://orcid.org/0000-0003-1999-5661)
- Vivek Singh (ORCID: https://orcid.org/0000-0003-3958-5635)
- Md Hasnat Ali
- Tejaswini Pingali
- Abhishek Sahoo (ORCID: https://orcid.org/0000-0003-4908-1852)
- Dilip Kumar Mishra (ORCID: https://orcid.org/0000-0002-5648-8362)
- Abhinav Reddy Kethiri (ORCID: https://orcid.org/0000-0001-9286-4591)
- Vijay Kumar Singh (ORCID: https://orcid.org/0000-0002-6005-8269)
- Harsha Agrwal
Institutions
- Manipal Academy of Higher Education (IN)
- L V Prasad Eye Institute (IN)
Publication Details
- Journal
- Experimental Eye Research
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1016/j.exer.2025.110378
- Citations
- 1
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.36