Transcriptome sequencing–based analysis of the molecular mechanism underlying the effect of lncRNA AC003090.1 on osteoporosis
FOXP1, as a molecular mediator of AC003090.1, affects the GSK-3β/β-catenin/c-Myc signaling pathway and promotes the osteogenic differentiation of hBMSCs, thus playing a key role in the progression of OP.
Authors
- Yizhong Li (ORCID: https://orcid.org/0000-0002-4950-5937)
- Xuedong Yao (ORCID: https://orcid.org/0000-0002-1328-3113)
- Huafeng Zhuang
- Youjia Xu (ORCID: https://orcid.org/0000-0002-9826-4324)
- Miao Zheng (ORCID: https://orcid.org/0000-0001-5026-8804)
- C. Q.-X. Lin
- Lin Yongjun
Institutions
- Fujian Medical University (CN)
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1186/s13018-025-05634-1
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Natural Science Foundation of Fujian Province