Porcine jejunal-derived extracellular vesicles participate in the regulation of lipid metabolism
Our findings suggest that jejunal-derived extracellular vesicles play a critical role in regulating lipid metabolism, and the regulatory effect of extracellular vesicles from obese piglets was higher than that of lean piglets. Furthermore, the different expression of miRNAs, such as miR-30b-5p, in intestinal extracellular vesicles may be the key to determining lipid deposition phenotypes across the two pig breeds.
Authors
- Yongliang Zhang (ORCID: https://orcid.org/0000-0003-4851-1662)
- Haibin Deng (ORCID: https://orcid.org/0000-0003-3626-0579)
- Jiajie Sun (ORCID: https://orcid.org/0000-0003-1992-154X)
- Junyi Luo (ORCID: https://orcid.org/0000-0002-1060-4081)
- Yaotian Fan
- Ting Chen (ORCID: https://orcid.org/0000-0003-1725-7956)
- Jiahao Zhu (ORCID: https://orcid.org/0009-0004-6271-4102)
- Qianyun Xi
Institutions
- South China Agricultural University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1186/s40104-025-01185-x
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Science and Technology Major Project