PRELIMINARY FINDINGS ON THE INFLUENCE OF WILD GARLIC EXTRACT ON CARDIOVASCULAR ISSUES IN PCOS RATS
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-age women, linked to cardiometabolic issues. Conventional treatments often fail to address PCOS’s complexity, prompting interest in alternatives like Allium ursinum L. (wild garlic), known for its therapeutic properties. This study evaluated the effects of wild garlic extract (500 mg/kg) on hemodynamic and echocardiographic parameters in a rat model of PCOS induced by letrozole and a high-fat diet. Results showed significant reductions in blood pressure, suggesting wild garlic may improve reproductive health and reduce cardiovascular risks associated with PCOS.
Authors
- Jovana Joksimović Jović (ORCID: https://orcid.org/0000-0002-8775-2752)
- Sladjana B. Novaković (ORCID: https://orcid.org/0000-0002-8737-5870)
- Vladimir Jakovljević (ORCID: https://orcid.org/0000-0002-0071-8376)
- Božidar Pindović (ORCID: https://orcid.org/0009-0000-7603-5865)
- Nikola Jović (ORCID: https://orcid.org/0000-0003-2366-3870)
- Aleksandar Kočović (ORCID: https://orcid.org/0000-0001-9906-436X)
- Vladimir Živković (ORCID: https://orcid.org/0000-0001-9354-9876)
- Teodora Todorović
- Isidora Milosavljević
- Milica Milinković Šorgić
- Jovan Milosavljević (ORCID: https://orcid.org/0009-0003-7799-6264)
- Maja Barudžija
Publication Details
- Published
- 2025-01-01
- DOI
- https://doi.org/10.46793/sbt30.73tt
- Primary Topic
- Garlic and Onion Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00