RBBP4 downregulation increases the sensitivity of A549 and HeLa cells to cisplatin by inhibiting cyclin D1 expression

This study showed that RBBP4 regulates the sensitivity of tumor cells to cisplatin and is a potential target for reversing cisplatin resistance in tumor cells.

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Publication Details

Journal
Clinics
Published
2025-01-01
DOI
https://doi.org/10.1016/j.clinsp.2025.100637
Citations
4
Primary Topic
Chemotherapy-induced organ toxicity mitigation
Type
article
Field-Weighted Citation Impact
5.89
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article

RBBP4 downregulation increases the sensitivity of A549 and HeLa cells to cisplatin by inhibiting cyclin D1 expression

Jingjing Zhong, Zhiyu Zeng, Meiqing Mai, Jinjun Rao et al.
4 citations
Clinics
Chemotherapy-induced organ toxicity mitigation
5.89
article

RBBP4 downregulation increases the sensitivity of A549 and HeLa cells to cisplatin by inhibiting cyclin D1 expression

Jingjing Zhong, Zhiyu Zeng, Meiqing Mai, Jinjun Rao, Zhiru Chen, Dandan Wang, Jie Ouyang
article en
4 citations

Abstract

This study showed that RBBP4 regulates the sensitivity of tumor cells to cisplatin and is a potential target for reversing cisplatin resistance in tumor cells.

ClinicsVol. 80
Jinan University (CN), Guangdong Pharmaceutical University (CN), Xiyuan Hospital (CN), Riverside Hospital of Guangxi Zhuang Autonomous Region (CN), Southern Medical University (CN)
Zero hunger
Openalex Percentile: Top 4%
Chemotherapy-induced organ toxicity mitigation
5.89
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