Generation and characterization of the iPSC line INDBi001-A from human keratinocytes of a healthy male using Sendai virus reprogramming

We generated a fully characterized iPSC line derived from human keratinocytes using Sendai virus-based reprogramming. This integration-free method preserves genomic integrity, enabling the generation of a pluripotent line with robust self-renewal and differentiation capabilities. Comprehensive characterization confirmed the iPSC line's pluripotency markers, trilineage differentiation potential, and karyotypic normality. This resource provides a valuable tool for disease modeling, drug discovery, and regenerative medicine applications.

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Publication Details

Journal
Stem Cell Research
Published
2025-04-06
DOI
https://doi.org/10.1016/j.scr.2025.103709
Citations
1
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
1.82

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article

Generation and characterization of the iPSC line INDBi001-A from human keratinocytes of a healthy male using Sendai virus reprogramming

Katharina Becker, Stefan Liebau, Kevin Achberger, Denise Sperlich et al.
1 citations
Stem Cell Research
Virus-based gene therapy research
1.82
article

Generation and characterization of the iPSC line INDBi001-A from human keratinocytes of a healthy male using Sendai virus reprogramming

Katharina Becker, Stefan Liebau, Kevin Achberger, Denise Sperlich, Ulrike A. Mau‐Holzmann
article en
1 citations

Abstract

We generated a fully characterized iPSC line derived from human keratinocytes using Sendai virus-based reprogramming. This integration-free method preserves genomic integrity, enabling the generation of a pluripotent line with robust self-renewal and differentiation capabilities. Comprehensive characterization confirmed the iPSC line's pluripotency markers, trilineage differentiation potential, and karyotypic normality. This resource provides a valuable tool for disease modeling, drug discovery, and regenerative medicine applications.

Stem Cell ResearchVol. 85
University of Tübingen (DE)
Deutsche Forschungsgemeinschaft
Zero hunger
Openalex Percentile: Top 17%
Virus-based gene therapy research
1.82
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Generation and characterization of the iPSC line INDBi001-A from human keratinocytes of a healthy male using Sendai virus reprogramming — Katharina Becker, Stefan Liebau, et al. · Stem Cell Research (2025) | TGRS Research Map | TGRS