Generation and characterization of the iPSC line INDBi001-A from human keratinocytes of a healthy male using Sendai virus reprogramming
We generated a fully characterized iPSC line derived from human keratinocytes using Sendai virus-based reprogramming. This integration-free method preserves genomic integrity, enabling the generation of a pluripotent line with robust self-renewal and differentiation capabilities. Comprehensive characterization confirmed the iPSC line's pluripotency markers, trilineage differentiation potential, and karyotypic normality. This resource provides a valuable tool for disease modeling, drug discovery, and regenerative medicine applications.
Authors
- Katharina Becker (ORCID: https://orcid.org/0000-0002-6479-3762)
- Stefan Liebau (ORCID: https://orcid.org/0000-0003-0721-8187)
- Kevin Achberger (ORCID: https://orcid.org/0000-0001-5706-6201)
- Denise Sperlich
- Ulrike A. Mau‐Holzmann (ORCID: https://orcid.org/0000-0002-4125-4643)
Institutions
- University of Tübingen (DE)
Publication Details
- Journal
- Stem Cell Research
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1016/j.scr.2025.103709
- Citations
- 1
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Deutsche Forschungsgemeinschaft