Phenotype, genotype, and laboratory assessment of congenital fibrinogen disorders: Data from the Rare Bleeding disorders in the Netherlands study
In patients with CFDs, postoperative bleeding correlates with fibrinogen activity, while female-specific bleeding affects all CFD subtypes. Elevated thrombin generation might explain thrombosis risk in these patients.
Authors
- Paul L. den Exter (ORCID: https://orcid.org/0000-0002-1543-5731)
- Bauke Haisma (ORCID: https://orcid.org/0009-0007-5149-8864)
- Joline L. Saes (ORCID: https://orcid.org/0000-0003-3219-4981)
- Marjon H. Cnossen (ORCID: https://orcid.org/0000-0003-1557-2995)
- Saskia E.M. Schols (ORCID: https://orcid.org/0000-0003-2423-2829)
- Laurens Nieuwenhuizen (ORCID: https://orcid.org/0000-0002-0494-9374)
- Nick van Es (ORCID: https://orcid.org/0000-0001-5256-6346)
- Karina Meijer (ORCID: https://orcid.org/0000-0001-9447-0465)
- Nicole M. A. Blijlevens (ORCID: https://orcid.org/0000-0002-1801-2072)
- Ilmar C. Kruis (ORCID: https://orcid.org/0000-0003-4118-4670)
- Waander L. van Heerde (ORCID: https://orcid.org/0000-0001-7101-8775)
- Sanna R. Rijpma
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Dutch Cancer Society (NL)
- Leiden University Medical Center (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Máxima Medisch Centrum (NL)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Netherlands Haemophilia Society
Publication Details
- Journal
- Thrombosis Research
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1016/j.thromres.2025.109317
- Citations
- 2
- Primary Topic
- Blood properties and coagulation
- Type
- article
- Field-Weighted Citation Impact
- 3.04