Toxicity of micromilimeter of polyvinly chloride and polystyrene sulfonic acid microplastics toward NCM460 cells

To investigate the difference in toxicity between polyvinyl chloride (PVC) and polystyrene sulfonic acid (PS), this study tests the toxicity of PVC and PS on NCM460 cells. NCM460 cells are located in the human colonic epithelium. By testing these two different microplastics at various concentrations and exposure times (e.g., 2 hours and 24 hours), the CCK-8 assay results show that PS is a safer material for intestinal cells than PVC. This work provides theoretical and experimental evidence for evaluating the risk of microplastics to intestinal cells.