Ablation Medical Devices with Chemical Technologies: Engineering aspects, System, Mechanism, and Future Directions.

Chemical ablation technology has emerged as a new method in minimally invasive medicine, providing specific and optimal treatment solutions for various diseases, including malignant tumors, cardiovascular diseases, renal denervation, and cardiac arrhythmia, by leveraging specially formulated cytotoxic agents delivered through precisely engineered devices. Chemical ablation minimizes collateral tissue damage while maximizing therapeutic outcomes. This paper offers a comprehensive overview of Ablation Medical Devices with Chemical Technologies, principles, critical system engineering considerations, applications, and the emerging role of computational modeling, notably finite element analysis (FEA) and fluid-structure interaction (FSI) in refining device design, optimizing, and enhancing procedure accuracy through engineering methods. Additionally, it addresses current challenges and outlines future directions, signaling an evolving, patient-centric era where the Ablation Medical Devices with Chemical Technologies stands to broaden its scope and impact significantly.