Harmine derivative H-2-168 induces the death of <i>Echinococcus granulosus</i> by regulating mitochondrial fusion and fission
<i>Drp1</i> is closely associated with mitochondrial fusion and fission, and H-2-168 may promote <i>E. granulosus</i> death through disrupting the balance between mitochondrial fusion and fission.
Authors
- Yuehong Gong (ORCID: https://orcid.org/0000-0002-7442-2885)
- Jianhua Wang (ORCID: https://orcid.org/0000-0001-6090-1300)
- Hao Wen (ORCID: https://orcid.org/0000-0001-7144-220X)
- Junpeng Liu (ORCID: https://orcid.org/0000-0001-9222-3663)
- Meiling Zhao
- Yicong Zhao (ORCID: https://orcid.org/0009-0008-1738-8335)
- Meichi Pan
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Pharmaceutical Biology
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1080/13880209.2025.2485898
- Primary Topic
- Parasitic infections in humans and animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Xinjiang Province