<b>Therapeutic effects of kecemcem leaves extract (<i>Spondias pinnata</i> (L.f.) Kurz) on LDL levels, cytokines, and microscopic liver changes in hyperlipidemic rat model</b>

Kecemcem leaves extract potentially reduced LDL, IL-1β, and TNF-α levels, increased IL-10 levels, and improved liver histology. This effect is supported by the flavonoid content of quercetin and catechin. Thus, kecemcem leaves extract has shown promising therapeutic effects in managing conditions related to hyperlipidemia and inflammation.

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Publication Details

Journal
Open Veterinary Journal
Published
2025-01-01
DOI
https://doi.org/10.5455/ovj.2025.v15.i3.22
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Therapeutic effects of kecemcem leaves extract (Spondias pinnata (L.f.) Kurz) on LDL levels, cytokines, and microscopic liver changes in hyperlipidemic rat model

‪Nunuk Dyah Retno Lastuti‬, Lia Cahya Sari, Ni Luh Ayu Megasari, Theresia Indah Budhy et al.
Open Veterinary Journal
Liver Disease Diagnosis and Treatment
article

Therapeutic effects of kecemcem leaves extract (Spondias pinnata (L.f.) Kurz) on LDL levels, cytokines, and microscopic liver changes in hyperlipidemic rat model

‪Nunuk Dyah Retno Lastuti‬, Lia Cahya Sari, Ni Luh Ayu Megasari, Theresia Indah Budhy, Yuliasih Yuliasih, Indra Prastiwi Jamaluddin
article en

Abstract

Kecemcem leaves extract potentially reduced LDL, IL-1β, and TNF-α levels, increased IL-10 levels, and improved liver histology. This effect is supported by the flavonoid content of quercetin and catechin. Thus, kecemcem leaves extract has shown promising therapeutic effects in managing conditions related to hyperlipidemia and inflammation.

Open Veterinary JournalVol. 15(0)
Universitas Airlangga (ID)
Good health and well-being
Openalex Percentile: Top 90%
Liver Disease Diagnosis and Treatment
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