Thrombophilia assessment: Experience of the hematology laboratory of IBN ROCHD AMC of Casablanca

Thrombophilia is a condition characterized by an increased tendency to thrombosis. It results from various etiologies often intertwined and involving both hereditary and acquired risk factors. In Morocco, there is a lack of data concerning thrombophilia at the national level and the declaration is not mandatory, the real prevalence of this pathology is impossible to determine. This study concerned patients who presented with thrombosis and whose thrombophilia assessments were carried out at the Hematology Laboratory of AMC Ibn Rochd in Casablanca. 80 assessments were compiled: The main indication that motivated the request for a thrombophilia assessment was DVT in 23 patients (28.75%), followed by ICVA in 20 patients (25%). The results were positive in 51.25% of cases: protein S deficiency was the most frequent (36.25%), anti-phospholipid antibodies were discovered in 2 patients. The diagnosis of venous thrombosis was made in 50 patients (62.5%), and the diagnosis of arterial thrombosis was made in 30 patients (37.5%), of which 20 patients (66.7%) had an ICVA. In our study, the predominant risk factor was PS deficiency unlike literary data in other Western countries which note APCR as the most frequent risk factor. This may be due to ethnic variability, hence the need for a larger multicenter study to confirm these results.