A French consensus proposal: Analytical performance targets for total and allergen-specific IgE and total tryptase
Precision medicine allows thorough characterization of patients endotype in allergy and anaphylaxis, thanks to progress in diagnostic tests and biomarkers. Allergy tests must therefore offer reliable, robust, and proficient quantitative results in each patient. These requirements have led to the development of quality assurance programs for allergy laboratory assays and their implementation in virtually all clinical laboratories performing in vitro allergy diagnosis and follow-up. However, consensus analytical performance targets for allergy assays have not yet been established. Here, the multicentric French network of public clinical laboratories and the Working Group on in vitro allergy diagnosis of the French Society of Allergy define performance criteria for specific and total IgE and tryptase tests.
Authors
- Barbara Seitz‐Polski (ORCID: https://orcid.org/0000-0002-8913-5969)
- Arnaud Cirée
- Thierry Tabary (ORCID: https://orcid.org/0000-0001-6301-589X)
- P.A. Apoil (ORCID: https://orcid.org/0000-0002-1057-4919)
- Delphine Giusti (ORCID: https://orcid.org/0000-0001-6857-4842)
- Joana Vitte (ORCID: https://orcid.org/0000-0002-3344-9408)
- Mirjana Radosavljevic (ORCID: https://orcid.org/0000-0003-3925-0640)
- Stéphanie Rogeau
- Julien Goret (ORCID: https://orcid.org/0000-0003-0469-169X)
- A. Sarrat
- Clotilde Amiot (ORCID: https://orcid.org/0000-0001-8496-2968)
- Caroline Hémont
- Valérie Guérin‐El Khourouj
- Anthony Léon
- Delphine Mariotte (ORCID: https://orcid.org/0000-0002-9989-4272)
- Marcelle Tonye‐Libyh
- P. Nicaise‐Roland (ORCID: https://orcid.org/0000-0002-4610-9226)
- Lionel Chollet
- Erwan Dumontet (ORCID: https://orcid.org/0000-0002-2438-7735)
- Bertrand Evrard (ORCID: https://orcid.org/0000-0001-5839-0695)
- Angélique Grenier
- C. Klingebiel (ORCID: https://orcid.org/0000-0002-9069-6931)
- Yannick Chantran (ORCID: https://orcid.org/0000-0002-9778-0044)
- Céline Beauvillain (ORCID: https://orcid.org/0000-0002-6987-3120)
- Moïse Michel (ORCID: https://orcid.org/0000-0002-0460-9898)
- Lorna Garnier
- Martine Pernollet
- Marie-Alexandra Alyanakian
- Mylène de Saint-Jore
- Marion Cremoni-Gauci
Institutions
- Hôpital Necker-Enfants Malades (FR)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Sorbonne Université (FR)
- Hôpital Armand-Trousseau (FR)
- Centre Hospitalier Universitaire de Besançon (FR)
- Centre Hospitalier Universitaire de Tours (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre hospitalier Emile Roux (FR)
- Centre Hospitalier Universitaire de Nîmes (FR)
- Centre Hospitalier Universitaire de Reims (FR)
- Centre Hospitalier Universitaire d'Angers (FR)
- Hôpital Lyon Sud (FR)
- Centre Hospitalier Universitaire de Caen Normandie (FR)
- Hôpital Robert-Debré (FR)
- Thion Medical (France) (FR)
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
- Hôpital Purpan (FR)
- Observatoire des Sciences de l’Univers Terre Homme Environnement Temps Astronomie (FR)
- Hôpital Bichat-Claude-Bernard (FR)
- Centre hospitalier Robert-Ballanger (FR)
- Centre Hospitalier Intercommunal Toulon-La Seyne-sur-Mer (FR)
- Centre Hospitalier Universitaire de Rennes (FR)
- Université de Rennes (FR)
- Université de Reims Champagne-Ardenne (FR)
- Université de Caen Normandie (FR)
Publication Details
- Journal
- Journal of Allergy and Hypersensitivity Diseases
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jahd.2025.100037
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00