Intranasal delivery of R8-modified circNFXL1 liposomes ameliorates Su5416-induced pulmonary arterial hypertension in C57BL/6 mice
R8-circNFXL1 liposomes offer a promising, targeted therapeutic strategy for PAH by addressing underlying molecular mechanisms. This approach has potential implications for developing alternative treatments to improve disease management and outcomes in PAH.
Authors
- Xin Jin (ORCID: https://orcid.org/0000-0002-7271-7655)
- Shaoyuan Huang
- Shanshan Li (ORCID: https://orcid.org/0000-0001-6443-958X)
- Ying Zhao (ORCID: https://orcid.org/0000-0002-7927-4906)
- Feifei Fan
- Miao Guo (ORCID: https://orcid.org/0000-0002-7080-8510)
- Xu Chen (ORCID: https://orcid.org/0000-0002-2632-7576)
- Houzhi Yang
Institutions
- Nankai University (CN)
- Tianjin Central Hospital of Gynecology Obstetrics (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1186/s12931-025-03203-y
- Citations
- 2
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China