Qingjie Fuzheng Granule prevents colitis-associated colorectal cancer by inhibiting abnormal activation of NOD2/NF-κB signaling pathway mediated by gut microbiota disorder
By mapping the relationships between CAC, immune responses, microbiota, and key pathways, this study clarifies the mechanism of QFG in inhibiting CAC, highlighting its potential for clinical use as preventive therapy.
Authors
- Shuzhong Yao (ORCID: https://orcid.org/0000-0002-5145-5705)
- Shihan Lin
- Wen Xu (ORCID: https://orcid.org/0000-0002-2327-0332)
- Tatyana Aleksandrovna Khrustaleva (ORCID: https://orcid.org/0000-0002-7272-4521)
- Yuxiang Qiu (ORCID: https://orcid.org/0009-0003-9210-405X)
- Jiumao Lin (ORCID: https://orcid.org/0000-0002-5312-6286)
- Ruiguo Wang (ORCID: https://orcid.org/0000-0003-0587-9993)
- Qiang Li (ORCID: https://orcid.org/0000-0002-9086-8502)
- Limin Chen (ORCID: https://orcid.org/0000-0002-4304-9037)
- Honglin An
- Bin Huang (ORCID: https://orcid.org/0000-0002-6668-4885)
- Mengxuan Gui
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- National Academy of Sciences of Belarus (BY)
- Institute of Physiology National Academy of Sciences of Belarus (BY)
Publication Details
- Journal
- Chinese Herbal Medicines
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1016/j.chmed.2025.04.001
- Citations
- 21
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 16.93
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province