Protopanaxatriol, a ginsenoside metabolite, induces apoptosis in colorectal cancer cells and arrests their cell cycle by targeting AKT
We are the first to demonstrate that the ginsenoside PPT can inhibit the activity of colon cancer cells by directly binding AKT.
Authors
- Jae Youl Cho (ORCID: https://orcid.org/0000-0001-8141-9927)
- Canglang Mou
- Jongsung Lee (ORCID: https://orcid.org/0000-0002-5073-2619)
- Yeye Hu
- Yuhao Wang (ORCID: https://orcid.org/0009-0001-2129-1762)
- Jong‐Hoon Kim (ORCID: https://orcid.org/0000-0003-3419-0538)
- Ziliang He (ORCID: https://orcid.org/0009-0003-7772-631X)
- Jianmei Zhang (ORCID: https://orcid.org/0000-0002-0694-4809)
Institutions
- Suzhou University of Science and Technology (CN)
- Jeonbuk National University (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-04-06
- DOI
- https://doi.org/10.1016/j.jgr.2025.03.012
- Citations
- 2
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Sungkyunkwan University