Operational Feasibility and Performance of mRPA Versus PCR for the Detection of HPV Types 16, 18, and 52 in Clinical Samples: An Exploratory Study
The findings suggest that mRPA could serve as a viable alternative to conventional PCR for HPV genotyping, offering advantages in speed and simplicity. Although mRPA's diagnostic performance was lower than PCR, its operational benefits make it particularly suitable for use in resource-limited settings. Future research should focus on further optimization and validation to enhance mRPA's diagnostic accuracy and explore its integration with user-friendly detection platforms.
Authors
- Didik Tulus Subekti (ORCID: https://orcid.org/0000-0002-2649-0242)
- Christina Safira Whinie Lestari (ORCID: https://orcid.org/0000-0001-5448-482X)
- Muhammad Ibrahim Desem (ORCID: https://orcid.org/0000-0003-4921-2031)
- Astri Rinanti (ORCID: https://orcid.org/0000-0001-8649-6307)
- Monica Dwi Hartanti (ORCID: https://orcid.org/0000-0001-7542-6434)
- Talitha Asmaria (ORCID: https://orcid.org/0000-0002-7192-7925)
- Endang Djuana (ORCID: https://orcid.org/0000-0002-2530-521X)
- Alvionita Kogoya
- Rahmi Amtha
- Raditya Wratsangka
- Ilham Hizbulloh
- Christopher Andrew Teguh
Institutions
- Universitas Trisakti (ID)
- National Research and Innovation Agency (ID)
Publication Details
- Journal
- International Journal of Women s Health
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijwh.s496621
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Trisakti
- Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi
- Direktorat Jenderal Pendidikan Tinggi