Influence of 3D printed and milled zirconia on the adhesion and viability of keratinocytes: An in vitro study

Both 3D printed and milled zirconia demonstrated good biocompatibility with human gingival keratinocytes. However, under extended direct surface contact, cells on 3D printed zirconia showed lower cell viability compared with milled zirconia. While 3D printed zirconia is promising for dental applications, further refinement of its surface properties and biocompatibility may be needed.

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Publication Details

Journal
Journal of Prosthetic Dentistry
Published
2025-04-05
DOI
https://doi.org/10.1016/j.prosdent.2025.03.020
Primary Topic
Additive Manufacturing and 3D Printing Technologies
Type
article
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article

Influence of 3D printed and milled zirconia on the adhesion and viability of keratinocytes: An in vitro study

Robert Boysen, Iris Frasheri, Jörg Lüchtenborg, A. Keßler et al.
Journal of Prosthetic Dentistry
Additive Manufacturing and 3D Printing Technologies
article

Influence of 3D printed and milled zirconia on the adhesion and viability of keratinocytes: An in vitro study

Robert Boysen, Iris Frasheri, Jörg Lüchtenborg, A. Keßler, Falk Schwendicke, Matthias Folwaczny, Nicolai Miosge, Olivia Hoefer
article en

Abstract

Both 3D printed and milled zirconia demonstrated good biocompatibility with human gingival keratinocytes. However, under extended direct surface contact, cells on 3D printed zirconia showed lower cell viability compared with milled zirconia. While 3D printed zirconia is promising for dental applications, further refinement of its surface properties and biocompatibility may be needed.

Journal of Prosthetic DentistryVol. 134(1)
University of Freiburg (DE), University Medical Center Freiburg (DE), LMU Klinikum (DE), Ludwig-Maximilians-Universität München (DE)
Zero hunger
Openalex Percentile: Top 94%
Additive Manufacturing and 3D Printing Technologies
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Influence of 3D printed and milled zirconia on the adhesion and viability of keratinocytes: An in vitro study — Robert Boysen, Iris Frasheri, et al. · Journal of Prosthetic Dentistry (2025) | TGRS Research Map | TGRS