Sequential combination with ropeginterferon alfa-2b and anti-PD-1 treatment as adjuvant therapy in HBV-related HCC: a phase 1 dose escalation trial

This phase I trial supports the safety and clinical efficacy of sequential treatment with ropeg and nivolumab in post-resection HBV-related HCC. This regimen holds promise for further adjuvant therapy trials in HCC, both HBV-related and other types.

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Publication Details

Journal
Hepatology International
Published
2025-04-05
DOI
https://doi.org/10.1007/s12072-025-10824-4
Citations
7
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
9.25
Controls
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article

Sequential combination with ropeginterferon alfa-2b and anti-PD-1 treatment as adjuvant therapy in HBV-related HCC: a phase 1 dose escalation trial

Albert Qin, Chan‐Yen Tsai, Ming‐Chih Ho, Pei‐Jer Chen et al.
7 citations
Hepatology International
Hepatocellular Carcinoma Treatment and Prognosis
9.25
article

Sequential combination with ropeginterferon alfa-2b and anti-PD-1 treatment as adjuvant therapy in HBV-related HCC: a phase 1 dose escalation trial

Albert Qin, Chan‐Yen Tsai, Ming‐Chih Ho, Pei‐Jer Chen, Chun‐Jen Liu
article en
7 citations

Abstract

This phase I trial supports the safety and clinical efficacy of sequential treatment with ropeg and nivolumab in post-resection HBV-related HCC. This regimen holds promise for further adjuvant therapy trials in HCC, both HBV-related and other types.

Hepatology InternationalVol. 19(3)
National Taiwan University (TW), National Taiwan University Hospital (TW)
Good health and well-being
Openalex Percentile: Top 2%
Hepatocellular Carcinoma Treatment and Prognosis
9.25
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