Multicenter evaluation of predictive clinical and imaging factors for pathological response in non-small cell lung cancer patients treated with neoadjuvant chemotherapy and immune checkpoint inhibitors

The combined application of clinical indicators including non-invasive tumor imaging and hematology can help clinicians to obtain a higher ability to predict NSCLC patient's pathological remission, and the effect is better than that of clinical factors alone. These findings could help guide personalized treatment strategies in this patient population.

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Publication Details

Journal
Cancer Immunology Immunotherapy
Published
2025-04-05
DOI
https://doi.org/10.1007/s00262-025-04017-z
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
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article

Multicenter evaluation of predictive clinical and imaging factors for pathological response in non-small cell lung cancer patients treated with neoadjuvant chemotherapy and immune checkpoint inhibitors

Zhenfa Zhang, Mengzhe Zhang, Shuai Jiang, Zekun Li et al.
Cancer Immunology Immunotherapy
Radiomics and Machine Learning in Medical Imaging
article

Multicenter evaluation of predictive clinical and imaging factors for pathological response in non-small cell lung cancer patients treated with neoadjuvant chemotherapy and immune checkpoint inhibitors

Zhenfa Zhang, Mengzhe Zhang, Shuai Jiang, Zekun Li, Yan Meng, Liu Zuo, Zhenfa Zhang
article en

Abstract

The combined application of clinical indicators including non-invasive tumor imaging and hematology can help clinicians to obtain a higher ability to predict NSCLC patient's pathological remission, and the effect is better than that of clinical factors alone. These findings could help guide personalized treatment strategies in this patient population.

Cancer Immunology ImmunotherapyVol. 74(5)
Tianjin Medical University Cancer Institute and Hospital (CN)
Good health and well-being
Openalex Percentile: Top 90%
Radiomics and Machine Learning in Medical Imaging
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