Natural, safety immunomodulatory derivatives of lactobacillus biofilms promote diabetic wound healing by metabolically regulating macrophage phenotype and alleviating local inflammation
The LBDs retains most bioactive components of the LB. As a natural, safe and immunomodulatory agent, LBDs promote diabetic wound healing by metabolically reprogramming macrophage phenotypes and improving the local immune microenvironment, offering promising potential for regenerative applications in diabetic wound management.
Authors
- Keqing Shi
- Tianling Chen
- Feifei Lian
- Junjie Chi (ORCID: https://orcid.org/0000-0002-0779-9287)
- Jiaojiao Chen (ORCID: https://orcid.org/0000-0002-7420-4052)
- Jian Xiao (ORCID: https://orcid.org/0000-0001-7374-6506)
- Jintao Yang (ORCID: https://orcid.org/0009-0004-8924-6046)
- Qingwei Zhou
- Abdullah Al Mamun (ORCID: https://orcid.org/0000-0002-8774-5616)
- Haijuan Zhang (ORCID: https://orcid.org/0000-0002-3710-7288)
- Jiali Guo (ORCID: https://orcid.org/0000-0002-6212-2383)
- Yibing Tao
- Yunmiao Ma
- Xiaoyu Dong (ORCID: https://orcid.org/0000-0001-9753-1104)
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Zhejiang Lab (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1016/j.jare.2025.04.001
- Citations
- 5
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.13