Sex Differences in Embolic Stroke of Undetermined Source: Echocardiographic Features and Clinical Outcomes

ESUS patients exhibit significant sex-based differences in echocardiographic features, with women showing larger LA and more valve abnormalities, while men present greater LV dysfunction. Female sex is independently associated with a lower risk of long-term mortality and a potentially higher risk of AFDAS. These findings underscore the need for individualized, sex-specific ESUS management strategies.

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Publication Details

Journal
European Journal of Neurology
Published
2025-04-01
DOI
https://doi.org/10.1111/ene.70133
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
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0.00
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article

Sex Differences in Embolic Stroke of Undetermined Source: Echocardiographic Features and Clinical Outcomes

Ghil Schwarz, Maria Sessa, Benedetta De Chiara, Andrea Bonelli et al.
European Journal of Neurology
Atrial Fibrillation Management and Outcomes
article

Sex Differences in Embolic Stroke of Undetermined Source: Echocardiographic Features and Clinical Outcomes

Ghil Schwarz, Maria Sessa, Benedetta De Chiara, Andrea Bonelli, Antonella Moreo, Chiara Ceresa, Angelo Cascio Rizzo
article en

Abstract

ESUS patients exhibit significant sex-based differences in echocardiographic features, with women showing larger LA and more valve abnormalities, while men present greater LV dysfunction. Female sex is independently associated with a lower risk of long-term mortality and a potentially higher risk of AFDAS. These findings underscore the need for individualized, sex-specific ESUS management strategies.

European Journal of NeurologyVol. 32(4)
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
Good health and well-being
Openalex Percentile: Top 88%
Atrial Fibrillation Management and Outcomes
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