<scp>IFI30</scp> Knockdown Inhibits <scp>ESCC</scp> Progression by Promoting Apoptosis and Senescence via Activation of <scp>JNK</scp> and <scp>P21</scp>/<scp>P16</scp> Pathways
This study suggests that IFI30 may regulate the JNK and P21/P16 pathways, exerting pro-tumorigenic effects in ESCC. IFI30 could serve as a potential novel target for ESCC treatment.
Authors
- Sisi Wei (ORCID: https://orcid.org/0000-0001-5959-653X)
- Baoen Shan (ORCID: https://orcid.org/0000-0003-2809-2042)
- Suli Dai (ORCID: https://orcid.org/0000-0003-2337-1149)
- Cong Zhang
- Zhe Zhang (ORCID: https://orcid.org/0000-0002-7488-078X)
- Yuhui Fu (ORCID: https://orcid.org/0000-0002-7487-4857)
- Chunhong Feng (ORCID: https://orcid.org/0000-0001-5914-1260)
- Lianmei Zhao (ORCID: https://orcid.org/0000-0002-9363-9588)
- Wenyao Xie
Institutions
- Hebei Medical University (CN)
- Handan College (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/1759-7714.70063
- Citations
- 1
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China