A randomized trial of open lung protective ventilation compared to conventional mechanical ventilation in deceased organ donors
An open lung protective ventilator strategy was safe but did not improve donor lung utilization or oxygenation compared to a conventional ventilator strategy in a population of US organ donors. NCT03439995.
Authors
- Jasleen Kukreja
- S. Weigt (ORCID: https://orcid.org/0000-0001-5351-8936)
- Ciara M. Shaver (ORCID: https://orcid.org/0000-0002-5677-0288)
- Lorraine B. Ware (ORCID: https://orcid.org/0000-0002-9429-4702)
- Jonathan Paul Singer (ORCID: https://orcid.org/0000-0003-0224-7472)
- Tatsuki Koyama (ORCID: https://orcid.org/0000-0002-8908-9165)
- Michael A. Matthay (ORCID: https://orcid.org/0000-0003-3039-8155)
- Julia A. Maheshwari (ORCID: https://orcid.org/0000-0002-2779-5929)
- Gundeep Dhillon (ORCID: https://orcid.org/0000-0003-0440-1138)
- Ahmad Salehi (ORCID: https://orcid.org/0000-0001-8257-3280)
- Nancy E. Wickersham
- John Nguyen (ORCID: https://orcid.org/0000-0002-9682-8675)
- Sharon Swain
Institutions
- University of California, Los Angeles (US)
- Palo Alto University (US)
- University of California, San Francisco (US)
- University of California System (US)
- Donor Network West (US)
- Vanderbilt University Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- The Journal of Heart and Lung Transplantation
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1016/j.healun.2025.03.027
- Citations
- 7
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 10.63
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute