Prediction of potential targets of aloe-emodin in the treatment of hepatocellular carcinoma using network pharmacology combined with bioinformatics
Based on network pharmacology, bioinformatics, molecular dynamics simulation, and in vitro experimental verification, we found that AE achieved a therapeutic effect on hepatocellular carcinoma by promoting apoptosis of hepatocellular carcinoma cells.
Authors
- Maoming Xiong
- Jianfeng Wei (ORCID: https://orcid.org/0000-0002-0302-4513)
- Haosong Chen
- Maoqi Xu
- Zhenglin Zhang (ORCID: https://orcid.org/0000-0002-5490-6815)
- Weiguo Zhou (ORCID: https://orcid.org/0000-0001-6703-5222)
- Jin Wang (ORCID: https://orcid.org/0000-0002-7957-5282)
- Wen Jiang (ORCID: https://orcid.org/0009-0001-4236-9952)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1007/s12672-025-02215-w
- Primary Topic
- Phytochemistry and biological activity of medicinal plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Anhui Provincial Key Research and Development Plan