Combination treatment of SGLT2i and GLP-1RA associated with improved cardiovascular outcomes in type 2 diabetes patients with acute coronary syndrome: A propensity score-matched cohort study

The combined use of SGLT2i and GLP-1RA was associated with a significantly decreased risk of MACE primarily driven by the lowering risks of all-cause mortality and nonfatal stroke in T2D patients with ACS, compared with SGLT2i use alone.

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Publication Details

Journal
International Journal of Cardiology
Published
2025-04-05
DOI
https://doi.org/10.1016/j.ijcard.2025.133229
Citations
16
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
20.72
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article

Combination treatment of SGLT2i and GLP-1RA associated with improved cardiovascular outcomes in type 2 diabetes patients with acute coronary syndrome: A propensity score-matched cohort study

Zeyuan Fan, Bing Xiao, Tao Liu, Yuntao Li et al.
16 citations
International Journal of Cardiology
Diabetes Treatment and Management
20.72
article

Combination treatment of SGLT2i and GLP-1RA associated with improved cardiovascular outcomes in type 2 diabetes patients with acute coronary syndrome: A propensity score-matched cohort study

Zeyuan Fan, Bing Xiao, Tao Liu, Yuntao Li, He Chang
article en
16 citations

Abstract

The combined use of SGLT2i and GLP-1RA was associated with a significantly decreased risk of MACE primarily driven by the lowering risks of all-cause mortality and nonfatal stroke in T2D patients with ACS, compared with SGLT2i use alone.

International Journal of CardiologyVol. 431
Aviation General Hospital (CN)
Good health and well-being
Openalex Percentile: Top 1%
Diabetes Treatment and Management
20.72
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Combination treatment of SGLT2i and GLP-1RA associated with improved cardiovascular outcomes in type 2 diabetes patients with acute coronary syndrome: A propensity score-matched cohort study — Zeyuan Fan, Bing Xiao, et al. · International Journal of Cardiology (2025) | TGRS Research Map | TGRS