Characteristic immune cell interactions in livers of children with acute hepatitis revealed by spatial single-cell analysis identify a possible postacute sequel of COVID-19
We identified a possible manifestation of an immune-mediated postacute sequel to COVID-19 associated with a characteristic immune infiltrate in children with AHUO. COVID-19 testing should be considered in paediatric AHUO.
Authors
- Andreas Vécsei (ORCID: https://orcid.org/0000-0001-6017-4625)
- Pius Martin
- Stephan W. Aberle
- Laurenz Krimmel (ORCID: https://orcid.org/0000-0002-8811-9289)
- Hubert Kogler (ORCID: https://orcid.org/0000-0003-1144-3387)
- Eberhard Lurz (ORCID: https://orcid.org/0000-0002-7479-7388)
- Martin Schwemmle (ORCID: https://orcid.org/0000-0002-2972-6855)
- Lisa Kern (ORCID: https://orcid.org/0000-0001-9365-4975)
- Bertram Bengsch (ORCID: https://orcid.org/0000-0003-2552-740X)
- Judith H. Aberle (ORCID: https://orcid.org/0000-0003-1197-3935)
- Henrike Salié (ORCID: https://orcid.org/0000-0002-2993-3782)
- Anne Gräser
- Vivien Karl (ORCID: https://orcid.org/0000-0001-7026-7622)
- Georg Friedrich Vogel (ORCID: https://orcid.org/0000-0002-2515-4490)
- Çiğdem Arıkan (ORCID: https://orcid.org/0000-0002-0794-2741)
- Muhammed Yüksel (ORCID: https://orcid.org/0000-0002-3390-6007)
- Herbert Tilg (ORCID: https://orcid.org/0000-0002-4235-2579)
- Maike Hofmann (ORCID: https://orcid.org/0000-0001-8410-8833)
- Isabel Gonçalves (ORCID: https://orcid.org/0000-0002-2935-0181)
- Robert Thimme (ORCID: https://orcid.org/0000-0003-1417-4135)
- Julia Vodopiutz (ORCID: https://orcid.org/0000-0002-8087-7026)
- Tobias Boettler (ORCID: https://orcid.org/0000-0002-1195-055X)
- Andreas Zollner (ORCID: https://orcid.org/0000-0001-6095-068X)
- Carolin Mogler (ORCID: https://orcid.org/0000-0003-3400-7254)
- Peter Hasselblatt (ORCID: https://orcid.org/0000-0002-1107-6516)
- Felix Röttele
- Thomas Müller (ORCID: https://orcid.org/0000-0001-8908-5589)
- Susana Nobre
- Felix Immanuel Maier
- Lena Woelfle
Institutions
- Koç University (TR)
- Innsbruck Medical University (AT)
- University of Freiburg (DE)
- German Cancer Research Center (DE)
- Universität Innsbruck (AT)
- University Medical Center Freiburg (DE)
- University Hospital Augsburg (DE)
- Hospitais da Universidade de Coimbra (PT)
- München Klinik (DE)
- St Anna Children's Hospital (AT)
- University Hospital Ulm (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Technical University of Munich (DE)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Gut
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1136/gutjnl-2024-333880
- Citations
- 2
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Deutsche Forschungsgemeinschaft