Trends and determinants of prescription of lithium and antidepressants for bipolar disorder in a large health care system between 2017 and 2022

Lithium remains underutilized even though it is a first-line treatment for BP, especially among certain sub-groups. Antidepressants are widely used to treat BP, often without mood stabilizers despite caution by most clinical guidelines. These findings underscore the need for continued efforts to promote use of best evidence-treatments for BP and reduce disparities in their use.

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Publication Details

Journal
Journal of Affective Disorders
Published
2025-04-05
DOI
https://doi.org/10.1016/j.jad.2025.04.006
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Trends and determinants of prescription of lithium and antidepressants for bipolar disorder in a large health care system between 2017 and 2022

Michael Albert, Catherine Steger, Fernando S. Goes, Peter P. Zandi et al.
1 links
Journal of Affective Disorders
Bipolar Disorder and Treatment
article

Trends and determinants of prescription of lithium and antidepressants for bipolar disorder in a large health care system between 2017 and 2022

Michael Albert, Catherine Steger, Fernando S. Goes, Peter P. Zandi, Shreeya Raghunath, Josina Straub, Sazal Sthapit, B Birckhead
article en

Abstract

Lithium remains underutilized even though it is a first-line treatment for BP, especially among certain sub-groups. Antidepressants are widely used to treat BP, often without mood stabilizers despite caution by most clinical guidelines. These findings underscore the need for continued efforts to promote use of best evidence-treatments for BP and reduce disparities in their use.

Journal of Affective DisordersVol. 381
Johns Hopkins University (US), Johns Hopkins Medicine (US)
Good health and well-being
Openalex Percentile: Top 92%
Bipolar Disorder and Treatment
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