Correlation Between Dissolution Profiles of Salt-Form Drugs in Biorelevant Bicarbonate Buffer and Oral Drug Absorption: Importance of Dose/ Fluid Volume Ratio
The use of clinical Dose/FV was important for improving the correlation between the biorelevant dissolution profiles and Fa for salt-form drugs.
Authors
- Yoshinao Tarumi
- Kiyohiko Sugano (ORCID: https://orcid.org/0000-0001-5652-1786)
- Yasuhiro HIGASHIGUCHI
Institutions
- Ritsumeikan University (JP)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1007/s11095-025-03854-y
- Citations
- 3
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 2.37
Funders
- Ritsumeikan University