Investigation of the Clinical Remission Course in Ulcerative Colitis from Tofacitinib Induction to Tapering or Withdrawal in Japanese Patients: A Single-Center Retrospective Study
In clinical practice, TOF 20 mg/day significantly induced induction of remission, and in patients who received 6 months of maintenance remission therapy with TOF 10 mg/day, the relapse rates between the TOF 10 mg/day maintenance group and the TOF withdrawal group were similar. After relapse, TOF 20 mg/day reintroduction therapy improved symptoms.
Authors
- Shinichi Nakamura
- Teppei Omori (ORCID: https://orcid.org/0000-0002-9959-5168)
- Ayumi Ito (ORCID: https://orcid.org/0000-0002-6035-8755)
- Katsutoshi Tokushige (ORCID: https://orcid.org/0000-0002-1004-7369)
- Yousuke Nakai (ORCID: https://orcid.org/0000-0001-7411-1385)
- Maria Yonezawa (ORCID: https://orcid.org/0000-0002-6692-4236)
- Miki Koroku
- Shun Murasugi (ORCID: https://orcid.org/0000-0003-1204-1806)
Institutions
- Kyorin University (JP)
- Tokyo Women's Medical University (JP)
Publication Details
- Journal
- Inflammatory Intestinal Diseases
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1159/000545704
- Citations
- 3
- Primary Topic
- Microscopic Colitis
- Type
- article
- Field-Weighted Citation Impact
- 4.06