Modulating the NLRP3 Inflammasome: Acitretin as a potential treatment for Sepsis-induced acute lung injury
Acitretin demonstrated significant anti-inflammatory properties through the suppression of the NLRP3 inflammasome, suggesting its potential as a therapeutic strategy for sepsis and related complications.
Authors
- Weifeng Li (ORCID: https://orcid.org/0000-0002-0244-2908)
- Haowen Xu
- Zhaocai Zhang (ORCID: https://orcid.org/0000-0002-4709-066X)
- Zhiyu Liang (ORCID: https://orcid.org/0000-0002-7678-9760)
- Shiying Sheng (ORCID: https://orcid.org/0000-0002-8900-4117)
- Huikang Xu
- Guang Liang (ORCID: https://orcid.org/0000-0002-8278-849X)
- Weiwei Luo (ORCID: https://orcid.org/0000-0002-1962-7714)
Institutions
- Second Affiliated Hospital of Zhejiang University (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.intimp.2025.114504
- Citations
- 2
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Zhejiang University
- National Key Research and Development Program of China