Comparison of different approaches in handling missing data in longitudinal multiple-item patient-reported outcomes: a simulation study
PPMs imputation at the item level was preferable for MNAR, whereas MMRM and MICE imputation at the item level were better for other scenarios. These findings provide valuable insight for selecting appropriate methods for handling missing PRO data.
Authors
- Chen Shi (ORCID: https://orcid.org/0000-0003-4328-7198)
- Chenguang Zhao (ORCID: https://orcid.org/0009-0006-3487-4015)
- Chun‐Quan Ou (ORCID: https://orcid.org/0000-0001-6866-7213)
- Lizhi Zhou (ORCID: https://orcid.org/0000-0001-7460-0787)
- Min-Qian Yan
Institutions
- Southern Medical University (CN)
Publication Details
- Journal
- Health and Quality of Life Outcomes
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1186/s12955-025-02364-0
- Citations
- 3
- Primary Topic
- Psychometric Methodologies and Testing
- Type
- article
- Field-Weighted Citation Impact
- 6.32
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province