Consecutive intrabronchial administration of Wharton’s jelly-derived mesenchymal stromal cells in ECMO-supported pediatric patients with end-stage interstitial lung disease: a safety and feasibility study (CIBA method)
Direct intrabronchial administration of MSC in a patient on ECMO is feasible and safe, and may be a new avenue to be assayed in ECMO patients with inflammatory, immunological and infectious diseases of the lung.
Authors
- Olga Serrano Garrote
- Olga Ordóñez
- Sergi Querol (ORCID: https://orcid.org/0000-0002-1105-8633)
- Aitor Gonzaga (ORCID: https://orcid.org/0000-0003-3040-5263)
- Bernat Soria (ORCID: https://orcid.org/0000-0002-2356-0380)
- Eduardo Fernández (ORCID: https://orcid.org/0000-0002-7052-6011)
- Cristina Prat‐Vidal (ORCID: https://orcid.org/0000-0002-5621-1101)
- A Castro Frontiñán
- Luis Blasco (ORCID: https://orcid.org/0000-0001-7484-2452)
- Etelvina Andreu (ORCID: https://orcid.org/0000-0003-0156-8944)
- Sylvia Belda Hofheinz (ORCID: https://orcid.org/0000-0002-4898-1413)
- Rodrigo Íñiguez (ORCID: https://orcid.org/0000-0002-2804-5038)
- Gema Martı́nez (ORCID: https://orcid.org/0000-0002-9795-2846)
- Rocío Morante Valverde
- María Salomé Albi Rodríguez
- Ana M. Gutiérrez‐Vílchez (ORCID: https://orcid.org/0000-0002-9310-4022)
- Luis Ignacio González‐Granado (ORCID: https://orcid.org/0000-0001-6917-8980)
- Nerea Domínguez‐Pinilla (ORCID: https://orcid.org/0000-0002-8452-7963)
- Nerea Castillo‐Flores
- María López Díaz
- Álvaro Gimeno Díaz de Atauri (ORCID: https://orcid.org/0000-0003-4775-892X)
- Margarita Blanco
- Cupuerán Yánez
- E. López
- Marga Anton-Bonete
- Clara Aymerich
- Xabier Freire
Institutions
- Universitat de Miguel Hernández d'Elx (ES)
- Research Institute Hospital 12 de Octubre (ES)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Hospital General Universitario de Alicante Doctor Balmis (ES)
- Banc de Sang i Teixits (ES)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1186/s13287-025-04289-3
- Citations
- 3
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 4.88
Funders
- Generalitat Valenciana
- Agencia Española de Medicamentos y Productos Sanitarios
- Université Toulouse III - Paul Sabatier
- Instituto de Salud Carlos III