IgG glycosylation profiling of systemic lupus erythematosus using lectin microarray
Patients with SLE show disease-specific alterations in serum IgG glycosylation, and aberrant Galβ3GalNAc, galactose and GalNAc glycosylation may have diagnostic value for SLE and NPSLE. Abnormal IgG glycans may provide new insights into their roles in SLE pathogenesis and progression.
Authors
- Xinping Tian (ORCID: https://orcid.org/0000-0002-1511-7952)
- Shangzhu Zhang
- Jiuliang Zhao (ORCID: https://orcid.org/0000-0001-9308-2858)
- Dong Xu (ORCID: https://orcid.org/0000-0002-6413-3043)
- Xiaofeng Zeng (ORCID: https://orcid.org/0000-0002-3883-2318)
- Qian Wang (ORCID: https://orcid.org/0000-0002-4171-9738)
- Qian Wang (ORCID: https://orcid.org/0000-0002-4541-9898)
- Yan Zhao (ORCID: https://orcid.org/0000-0001-7279-3829)
- Yang Wu (ORCID: https://orcid.org/0000-0002-0650-7713)
- Chaojun Hu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- Lupus Science & Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/lupus-2024-001413
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Peking Union Medical College Hospital
- Beijing Municipal Science and Technology Commission
- Chinese Academy of Medical Sciences Initiative for Innovative Medicine