Management of Bilateral Corneal Perforation Complicating Rheumatoid Arthritis: A Case Report

Rheumatoid arthritis (RA) can lead to severe ophthalmological complications, particularly peripheral ulcerative keratitis (PUK), which may progress to corneal perforation, threatening both functional and anatomical prognosis. We report the case of a 65-year-old patient with erosive and deforming RA who developed bilateral corneal perforation. Management required a multidisciplinary approach combining medical and surgical treatments, including amniotic membrane transplantation and anti-TNF biotherapy. The outcome was marked by satisfactory corneal healing and partial functional improvement. This case highlights the importance of early diagnosis and appropriate management to optimize visual prognosis.

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Publication Details

Journal
Ophthalmology Research An International Journal
Published
2025-04-05
DOI
https://doi.org/10.9734/or/2025/v20i1450
Primary Topic
Osteomyelitis and Bone Disorders Research
Type
article
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article

Management of Bilateral Corneal Perforation Complicating Rheumatoid Arthritis: A Case Report

Y. EL KHALIFA, abdeljalil Moutaouakil, I. HAJJI, S. Belghmaidi et al.
Ophthalmology Research An International Journal
Osteomyelitis and Bone Disorders Research
article

Management of Bilateral Corneal Perforation Complicating Rheumatoid Arthritis: A Case Report

Y. EL KHALIFA, abdeljalil Moutaouakil, I. HAJJI, S. Belghmaidi, S. Rachda
article en

Abstract

Rheumatoid arthritis (RA) can lead to severe ophthalmological complications, particularly peripheral ulcerative keratitis (PUK), which may progress to corneal perforation, threatening both functional and anatomical prognosis. We report the case of a 65-year-old patient with erosive and deforming RA who developed bilateral corneal perforation. Management required a multidisciplinary approach combining medical and surgical treatments, including amniotic membrane transplantation and anti-TNF biotherapy. The outcome was marked by satisfactory corneal healing and partial functional improvement. This case highlights the importance of early diagnosis and appropriate management to optimize visual prognosis.

Ophthalmology Research An International JournalVol. 20(1)
Centre Hospitalier Universitaire Mohammed VI (MA), Mohamed I University (MA)
Openalex Percentile: Top 90%
Osteomyelitis and Bone Disorders Research
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Management of Bilateral Corneal Perforation Complicating Rheumatoid Arthritis: A Case Report — Y. EL KHALIFA, abdeljalil Moutaouakil, et al. · Ophthalmology Research An International Journal (2025) | TGRS Research Map | TGRS