Genomics guiding personalized first-line immunotherapy response in lung and bladder tumors
These findings reveal promising biomarkers and mechanistic insights, offering a new perspective on predicting ICI response and opening up exciting possibilities for more personalized immunotherapy strategies in NSCLC and MIBC.
Authors
- Laura Juaneda‐Magdalena (ORCID: https://orcid.org/0000-0002-5450-0014)
- Ihab Abdulkader (ORCID: https://orcid.org/0000-0003-1247-2331)
- Jenifer Brea-Iglesias
- Ana Oitabén (ORCID: https://orcid.org/0000-0002-4877-6145)
- María Gallardo‐Gómez (ORCID: https://orcid.org/0000-0002-4856-9322)
- Carmé García-Benito (ORCID: https://orcid.org/0000-0003-2583-8769)
- Laura Muinelo
- Martín Lázaro-Quintela (ORCID: https://orcid.org/0000-0002-0657-4713)
- João M. Alves (ORCID: https://orcid.org/0000-0002-9599-5463)
- Mónica Martínez‐Fernández (ORCID: https://orcid.org/0000-0003-1251-0748)
- Luis León‐Mateos (ORCID: https://orcid.org/0000-0002-0742-1209)
- Jesús María Paramio (ORCID: https://orcid.org/0000-0001-7520-3177)
- Manuel Pino-González
Institutions
- Universidad Complutense de Madrid (ES)
- Universidade de Santiago de Compostela (ES)
- Galicia Sur Biomedical Foundation (ES)
- Complejo Hospitalario Universitario de Santiago (ES)
- Center for Research in Molecular Medicine and Chronic Diseases (ES)
- Instituto de Investigación Sanitaria de Santiago (ES)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
- Universidade de Vigo (ES)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1186/s12967-025-06323-7
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundación Científica Asociación Española Contra el Cáncer
- Ministerio de Ciencia e Innovación
- Axencia Galega de Innovación
- Xunta de Galicia
- Instituto de Salud Carlos III
- European Regional Development Fund