Oncogenic and immunological functions of USP35 in pan-cancer and its potential as a biomarker in kidney clear cell carcinoma
USP35 is overexpressed in KIRC and associated with poor prognosis, likely promoting tumor progression through oncogenic pathways and immune modulation. Its correlation with drug sensitivity positions USP35 as a potential therapeutic target, warranting further investigation into its mechanistic functions and therapeutic applications.
Authors
- Zezhi Shan
- Yadong Guo (ORCID: https://orcid.org/0000-0002-6684-7015)
- Xudong Yao (ORCID: https://orcid.org/0000-0001-6207-8514)
- Wentao Zhang (ORCID: https://orcid.org/0000-0002-5733-4875)
- Ziyang Zhou (ORCID: https://orcid.org/0000-0003-0154-6948)
- Ziyou Lin (ORCID: https://orcid.org/0000-0002-3657-5004)
- Pengfei Wu (ORCID: https://orcid.org/0000-0001-7621-5970)
- Shiyu Mao (ORCID: https://orcid.org/0000-0003-4652-6828)
Institutions
- Tongji University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1186/s12885-025-13964-w
- Citations
- 2
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.04