Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea

Our findings are the first to show that m6A-modified circRNAs play a key role in OSA-induced cardiovascular disease. This study highlights the pivotal role of m6A-modified circRNAs in regulating gene expression and their potential implications in understanding the molecular pathogenesis of OSA-induced cardiac injury.

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Publication Details

Journal
BMC Pulmonary Medicine
Published
2025-04-05
DOI
https://doi.org/10.1186/s12890-025-03609-w
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.00

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article

Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea

James H. Lan, Qingshi Chen, Yuhui Wang, Chang Liu et al.
BMC Pulmonary Medicine
RNA modifications and cancer
article

Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea

James H. Lan, Qingshi Chen, Yuhui Wang, Chang Liu, Hongli Chen
article en

Abstract

Our findings are the first to show that m6A-modified circRNAs play a key role in OSA-induced cardiovascular disease. This study highlights the pivotal role of m6A-modified circRNAs in regulating gene expression and their potential implications in understanding the molecular pathogenesis of OSA-induced cardiac injury.

BMC Pulmonary MedicineVol. 25(1)
Fujian Medical University (CN), Second Affiliated Hospital of Fujian Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Fujian Province, Fujian Medical University, Fujian Provincial Health Commission, Science and Technology Bureau of Quanzhou
Good health and well-being
Openalex Percentile: Top 94%
RNA modifications and cancer
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Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea — James H. Lan, Qingshi Chen, et al. · BMC Pulmonary Medicine (2025) | TGRS Research Map | TGRS