Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the <scp>AIDA</scp> Network Uveitis Registry
ADA monotherapy could be equally effective as its combination with MTX in both preventing uveitis relapses and preserving visual acuity in paediatric NIU, with comparable retention rates over 36 months of treatment. The steroid-sparing effect of ADA monotherapy warrants further extensive evaluation to define its optimal placement in the therapeutic strategy for paediatric NIU.
Authors
- Adele Civino (ORCID: https://orcid.org/0000-0002-0416-768X)
- Kalpana Babu Murthy
- Stefano Gentileschi (ORCID: https://orcid.org/0000-0001-9682-4706)
- Bruno Frediani (ORCID: https://orcid.org/0000-0002-9375-5984)
- Gaafar Ragab (ORCID: https://orcid.org/0000-0001-6529-0334)
- Maria Pia Paroli (ORCID: https://orcid.org/0000-0002-4395-4774)
- Rana Hussein Amin (ORCID: https://orcid.org/0000-0003-3346-8067)
- Maria Francesca Gicchino (ORCID: https://orcid.org/0000-0003-0329-6583)
- Francesca Minoia (ORCID: https://orcid.org/0000-0002-5093-8422)
- Ester Carreño (ORCID: https://orcid.org/0000-0002-0055-9547)
- Maria Sole Chimenti (ORCID: https://orcid.org/0000-0002-1343-1729)
- Emanuela Del Giudice (ORCID: https://orcid.org/0000-0002-3334-4884)
- Valeria Caggiano (ORCID: https://orcid.org/0000-0002-9907-4856)
- Antonio Vitale (ORCID: https://orcid.org/0000-0003-4469-7332)
- Lampros Fotis (ORCID: https://orcid.org/0000-0001-7171-6119)
- Paola Saboya‐Galindo (ORCID: https://orcid.org/0009-0009-2159-2459)
- Maria Tarsia (ORCID: https://orcid.org/0000-0002-1287-5854)
- Silvana Guerriero (ORCID: https://orcid.org/0000-0002-6545-2273)
- Alex Fonollosa (ORCID: https://orcid.org/0000-0002-1521-7144)
- Gian Marco Tosi (ORCID: https://orcid.org/0000-0001-9289-1717)
- Luca Cantarini (ORCID: https://orcid.org/0000-0002-7352-1275)
- Francesco La Torre (ORCID: https://orcid.org/0000-0002-5235-2900)
- Germán Mejía‐Salgado (ORCID: https://orcid.org/0000-0002-1241-0715)
- Angela Mauro (ORCID: https://orcid.org/0000-0002-7008-3409)
- Soad Hashad (ORCID: https://orcid.org/0000-0003-0500-7458)
- Alejandra de‐la‐Torre (ORCID: https://orcid.org/0000-0003-0684-1989)
- Vishali Gupta (ORCID: https://orcid.org/0000-0001-8216-4620)
- Saverio La Bella (ORCID: https://orcid.org/0000-0002-1244-0789)
- Jurgen Sota (ORCID: https://orcid.org/0000-0002-7549-2922)
- Mohamed Tharwat Hegazy (ORCID: https://orcid.org/0000-0002-2939-5611)
- Carla Gaggiano (ORCID: https://orcid.org/0000-0003-1401-8343)
- Claudia Fabiani (ORCID: https://orcid.org/0000-0003-4515-7741)
- Luciana Breda (ORCID: https://orcid.org/0000-0002-1088-524X)
- Stefania Costi (ORCID: https://orcid.org/0000-0002-4468-6839)
- Rosanna Dammacco (ORCID: https://orcid.org/0000-0002-5604-4876)
- Maria Cristina Maggio
- Marco Cattalini
- Giuseppe Lopalco
- María Andrea Bernal‐Valencia
- Halah Etayari
Institutions
- University of Siena (IT)
- University of Rome Tor Vergata (IT)
- Cairo University (EG)
- University of the Basque Country (ES)
- University of Campania "Luigi Vanvitelli" (IT)
- National and Kapodistrian University of Athens (GR)
- University of Tripoli (LY)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- BioCruces Health research Institute (ES)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Hospital Universitario Fundación Jiménez Díaz (ES)
- Hospital de Cruces (ES)
- Ospedale Pediatrico Giovanni XXIII (IT)
- Ospedale SS. Annunziata (IT)
- Ospedale Vito Fazzi (IT)
- ASST Fatebenefratelli Sacco (IT)
- Post Graduate Institute of Medical Education and Research (IN)
- University of Bari Aldo Moro (IT)
- University of Brescia (IT)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
- Universidad del Rosario (CO)
Publication Details
- Journal
- Clinical and Experimental Ophthalmology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1111/ceo.14534
- Citations
- 4
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 6.83
Funders
- Università degli Studi di Siena