Effectiveness, Safety, and Pharmacokinetics of Linezolid in Pediatric Bacterial Central Nervous System Infections
Linezolid demonstrated favorable clinical efficacy and tolerability in pediatric CNSIs, with CSF concentrations that correlated with plasma levels and exhibited predictable pharmacokinetics.
Authors
- Xin-Xin I. Zeng (ORCID: https://orcid.org/0000-0002-2707-7759)
- Shanshan Xu (ORCID: https://orcid.org/0000-0002-8019-9819)
- Lisu Huang (ORCID: https://orcid.org/0000-0001-8193-7353)
- Xuben Yu (ORCID: https://orcid.org/0000-0003-1897-4519)
- Yi Shi (ORCID: https://orcid.org/0000-0001-5566-9471)
- Yuhang Wu (ORCID: https://orcid.org/0000-0002-4339-0753)
- Lvchang Zhu
- Xiaoshan Zhang (ORCID: https://orcid.org/0009-0003-2797-346X)
Institutions
- Shanghai Jiao Tong University (CN)
- Wenzhou Medical University (CN)
- XinHua Hospital (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- National Clinical Research (US)
- Zhejiang University (CN)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1093/infdis/jiaf169
- Citations
- 2
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- National Health Commission of the People's Republic of China