Significantly Increased Aqueous Solubility of Piperine via Nanoparticle Formulation Serves as the Most Critical Factor for Its Brain Uptake Enhancement.
Our findings suggested that increasing solubility rather than changing the administration route served as the most critical step to enhance the brain uptake of piperine.
Authors
- Sharon Shui Yee Leung (ORCID: https://orcid.org/0000-0002-0194-7058)
- Zhong Zuo (ORCID: https://orcid.org/0000-0002-6976-6157)
- Jiahao Li (ORCID: https://orcid.org/0000-0002-4107-7720)
- Cuiping Jiang (ORCID: https://orcid.org/0000-0001-9694-5399)
- Edwin Chan
- Evelyn Tze Yin Ho
Institutions
- University of California, Santa Barbara (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2147/ijn.s506827
- Citations
- 1
- Primary Topic
- Piperaceae Chemical and Biological Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.56