Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys

Androgen bioactivity was undetectable before pubertal onset but measurable after in most boys, reflecting both the bioassay's lower sensitivity and potential physiological changes in androgen bioactivity during early puberty. Further studies are needed to clarify these observations.

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Publication Details

Journal
Clinical Endocrinology
Published
2025-04-04
DOI
https://doi.org/10.1111/cen.15249
Primary Topic
Hormonal and reproductive studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys

Jørgen Holm Petersen, Anna‐Maria Andersson, Anne Jørgensen, Frank Claessens et al.
Clinical Endocrinology
Hormonal and reproductive studies
article

Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys

Jørgen Holm Petersen, Anna‐Maria Andersson, Anne Jørgensen, Frank Claessens, Leen Antonio, Anders Juul, Dirk Vanderschueren, Trine Holm Johannsen, Lise Aksglæde, Katrine Harpelunde Poulsen, Andrés Felipe Østergaard Fritzbøger
article en

Abstract

Androgen bioactivity was undetectable before pubertal onset but measurable after in most boys, reflecting both the bioassay's lower sensitivity and potential physiological changes in androgen bioactivity during early puberty. Further studies are needed to clarify these observations.

Clinical EndocrinologyVol. 103(2)
University of Copenhagen (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK), KU Leuven (BE)
Novo Nordisk, Novo Nordisk Fonden
Good health and well-being
Openalex Percentile: Top 91%
Hormonal and reproductive studies
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Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys — Jørgen Holm Petersen, Anna‐Maria Andersson, et al. · Clinical Endocrinology (2025) | TGRS Research Map | TGRS