Rapid Differentiation of False Positives of Galactomannan Related to Contaminated Intravenous Fluids via a Pharmacokinetics Model and Innovative Web-Based Tool
This study developed a pharmacokinetic model and web-based tool to distinguish true invasive aspergillosis from false positives caused by contaminated fluids. By analyzing galactomannan kinetics, false positives were identified within 24 hours, improving diagnostic accuracy and aiding clinicians in early decision making while minimizing unnecessary interventions.
Authors
- Suein Choi (ORCID: https://orcid.org/0000-0001-5438-7819)
- Dukhee Nho (ORCID: https://orcid.org/0000-0003-2800-636X)
- Raeseok Lee (ORCID: https://orcid.org/0000-0002-1168-3666)
- Seunghoon Han (ORCID: https://orcid.org/0000-0002-9976-5120)
- Dong‐Gun Lee (ORCID: https://orcid.org/0000-0003-4655-0641)
- Sung‐Yeon Cho (ORCID: https://orcid.org/0000-0001-5392-3405)
Institutions
- Catholic University of Korea (KR)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1093/ofid/ofaf088
- Primary Topic
- Polysaccharides and Plant Cell Walls
- Type
- article
- Field-Weighted Citation Impact
- 0.00